Portal for ArcGIS uses certain ports to communicate. Below is a description of the ports that you may need to allow on your firewall.
HTTP port 7080
Portal for ArcGIS communicates through port 7080, and you must ensure that your firewall allows HTTP communication through this port. When configuring the Web Adaptor for use with your portal, you'll reference the HTTP URL, for example, http://portal.domain.com:7080.
HTTPS port 7443
By default, Portal for ArcGIS uses the HTTPS port 7443 to encrypt communication that requires user credentials. When credentials are not required, HTTP is used. If you have configured your portal to use SSL for all communication, only HTTPS is used. For more information, see Configuring HTTPS.
Internally used ports 7005, 7099, 7199, and 7654
Ports 7005, 7099, 7199, and 7654 are used internally by Portal for ArcGIS. You must ensure that your firewall allows local communication on these ports and they are not currently in use by another application.